CambridgeSoft's ChemOffice Professional is currently the world's top-class desktop chemical software suite. It integrates 20+ powerful and professional chemistry related applications in one place, and provides you with an excellent, complete chemical assistant system, which enables your research work to reach a new level.

ChemOffice Professional consists of a series of relatively independent tools, primarily including ChemDraw (chemical structure drawing), Chem3D (molecular model and simulation), ChemFinder (chemical information searching & integrating system). With them, we can directly convert the name of some compound into 3D structure chart, so as to save trouble on drawing it out; Conversely, it can give the correct name of some compound with known structure, etc. Moreover, ChemOffice Professional also comes with a full set of ChemInfo database, ChemACX, ChemACX-SC, Merck indexes, ChemMSDX, and so on.

At first, ChemOffice Professional was only designed and developed for scientific researchers' personal use in the fields of chemical or biological research. But now, it supports sharing of solutions, which can bring many benefits to all scientific and technical workers in many research institutions.

Built-in Applications

  • ChemDraw Professional
  • ChemDraw Cloud
  • ChemDraw E-Notebook
  • Chem3D
  • ChemFinder Ultra
  • BioViz
  • ChemDraw for Excel
  • ChemFinder for Office
  • CombiChem for Excel
  • Enhanced Retrosynthesis Tool
  • BioDraw
  • ChemNMR
  • Struct=Name
  • ChemScript
  • MOPAC2016 Interface for Chem3D 15
  • Autodock Interface
  • CONFLEX Interface
  • GAMESS and GAMESS Interface
  • Gaussian Interface
  • ChemDraw ActiveX/Plugin Pro

Key Features

Application Feature
ChemDraw Professional
  • ActiveX Edit in ChemDraw
  • Arrows Tool
  • BioDraw
  • Biopolymer Toolbar
  • Chain Tools
  • ChemBio3D HotLink
  • Chemical File Format
  • Chemical Warnings
  • ChemNMR Solvent Selection
  • ChemNMR User Proton Shift Database
  • ChemProp
  • CLogP
  • Custom Templates & Nicknames
  • Database HotLink
  • Expand Generic Structure
  • Floating Character Map
  • Floating Periodic Table
  • Freehand Drawing Tool
  • Gel Electrophoresis Plate Tool
  • High Color Documents and Templates
  • ISIS-style Data SGroups
  • LabArt
  • LogP
  • LogS
  • Mass & Other Fragmentation Tools
  • MS Office Integration
  • Multi-Page Docs
  • Name=Struct
  • Online Menu
  • Paste Sequences
  • pKa
  • Plasmid Map Tool
  • Polymer Draw
  • Properties HotLink
  • Relative Stereochemistry
  • Rotation about Arbitrary Centers
  • Search SciFinder
  • Sequence Tool
  • Stereochemistry
  • Stoichiometry Grid
  • Structure CleanUp
  • Structure Perspective Tool
  • TLC Plate Tool
  • tPSA
Chem3D
  • Autodock Interface
  • Automatic Overlay
  • ChemDraw HotLink
  • ChemProp
  • CLogP
  • CONFLEX Interface
  • Dihedral Driver
  • Enhanced Graphics
  • Formal Charges
  • GAMESS plus Interface
  • Group Labels
  • Hydrogen Bonds
  • Kekule / Delocalized Display Mode
  • LogP
  • LogS
  • MM2
  • MMFF94
  • Model Explorer
  • Molecular Modeling & Dynamics
  • MOPAC Interface
  • Partial Surfaces
  • pKa
  • Spectrum Viewer
  • Stochastic Conformational Analysis
  • Structure Browser
ChemFinder Ultra
  • 3D Query/Finder
  • ActiveX Control Boxes
  • Automatic Form Generation
  • BioViz
  • ChemFinder for Office
  • Chemical Searching
  • Clustering Analysis
  • Compound Profiles
  • Hit List and Query Management
  • List Merge
  • Multiple Data Views
  • Plotting
  • Plotting: Statistical Analysis and Customization
  • Plotting: Subform Plots
  • Property Generation
  • Python Scripting
  • Scripting
  • Standardized Handling of Implict Hydrogens
  • Subforms
  • Tabbed Forms
ChemDraw for Excel
  • ChemDraw/Excel
  • Name>Struct/Excel
BioDraw
  • BioDraw
  • Biopolymer Toolbar
  • Floating Character Map
  • Freehand Drawing Tool
  • High Color Templates
  • MS Office Integration
  • Plasmid Map Tool
  • Polymer Draw
ChemNMR
  • ChemNMR
  • ChemNMR User Proton Shift Database
Struct=Name
  • Name>Struct
  • Struct>Name
ChemScript ChemScript Pro
Gaussian Interface Gaussian Interface
ChemDraw ActiveX/Plugin Pro
  • ActiveX Edit in ChemDraw
  • Arrows Tool
  • Chemical File Format
  • Chemical Warnings
  • Custom Templates & Nicknames
  • Expand Generic Structure
  • Floating Character Map
  • Floating Periodic Table
  • Freehand Drawing Tool

About ChemDraw Professional 

ChemDraw Professional is currently the best and most popular chemical structure drawing tool in the world. Meanwhile, it is also one of 3 most important members in CambridgeSoft's ChemOffice series of software, the other two are Chem 3D (molecular structure model) and ChemFinder (chemical information database).

ChemDraw Professional provides a complete and easy-to-use set of solutions for chemical drawings. This includes compound formula, chemical reaction equation, chemical flow chart, plane figure commonly used in chemical fields such as simple experiment device. In short, with ChemDraw Professional, you can easily, quickly draw and edit all figures related to chemistry. And because it came with a lot of international authoritative journals, in recent years, it has become the standard of drawing chemical charts for publications, articles, reports in chemical industry, CAI software and some other related areas.

In brief, ChemDraw Professional is an extremely helpful must-have tool for any chemical industry practitioners, especially for chemical workers who are involved in chemical structures.

System Requirements

v15.x & v16.x Universal Activation Codes 

Name AppNee.com
Company/Organization AppNee Freeware Group.
Email address [email protected]
Serial Number
  • 875-335031-8691
  • 875-385499-9864
Activation Code
  • JPZ-R7XLV-KN-NXKU-TFKAV-4H2K-VKFAI
  • 6UE-7IMW3-5W-QZ5P-J3PCX-OHDX-35GRN

Edition Statement

AppNee provides the ChemOffice Professional Edition full installers, universal activation codes, and unlocked files for Windows 32-bit and 64-bit.

Installation Notes

for 23.1.1:
  1. Install program (choose custom install, uncheck "ChemDraw Collections"), and install x64 version only
  2. Copy unlocked files to installation folder like "C:\Program Files\RevvitySignalsSoftware\ChemDrawApplications\" and overwrite
  3. Enter the path like "C:\Program Files\RevvitySignalsSoftware\ChemDrawApplications\Common\DLLs\"
  4. Rename "FlxComm64.dll" and "FlxCore64.dll" to "FlxComm64.dll.bak" and "FlxCore64.dll.bak"
  5. Double click all reg key files to import license info
  6. Block this program or use it offline
  7. Run ChemDraw, choose "Activation code" option in the licensing window
  8. Done
for v17.1+:
  1. Run setup and click 'Install Software'
  2. Click 'Quit' -> 'OK' when the "PerkinElmer Software Activation" dialog pops up
  3. Finish installation
  4. Copy the unlocked files to installation folder and overwrite
  5. Done
*** Do not update program.

for v17.0:

  1. Install ChemOffice, and click 'Quit' button in the activation dialog to continue installation
  2. After installation, copy the unlocked file 'CambridgeSoft.ChemOffice.ChemDrawExcel.LibChemDrawWrapper.dll' to installation directory
  3. Copy the other unlocked files (Chem3D.exe, ChemDraw.exe, ChemFinder.exe, ChemFinderForOffice.exe) to the following paths and overwrite
    • X:\Program Files\ChemOffice2017\Chem3D
    • X:\Program Files\ChemOffice2017\ChemDraw
    • X:\Program Files\ChemOffice2017\ChemFinder
  4. Done
for v15.x, v16.x:
  1. First, disable your Internet connection
  2. Run ChemDraw Professional full setup, and use the activation code above to register ChemOffice Professional
  3. Finish the rest of installation process
  4. All done, enjoy!
*** You'd better block ChemDraw Professional via your firewall.

Download URLs

License Version Download Size
Professional Edition v15.0 reserved n/a
v16.0 reserved 348 MB
v17.1 376 MB
v22.2.0 711 MB
v23.1.1 1.30 GB
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